• Kobayashi H, Tohyama S, Kanazawa H, Ichimura H, Chino S, Tanaka Y, Suzuki Y, Zhao J, Shiba N, Kadota S, Narita K, Naito T, Seto T, Kuwahara K, Shiba Y, Fukuda K. Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration. J Mol Cell Cardiol 174:77-87, 2023
• Hamatani Y, Kato T, Morimoto T, Iguchi M, Yaku H, Inuzuka Y, Kitai T, Nagao K, Tamaki Y, Yamamoto E, Ozasa N, Yamashita Y, Abe M, Sato Y, Kuwahara K, Akao M, Kimura T; KCHF Registry investigators. Association of intravenous heparin administration with in-hospital clinical outcomes among hospitalized patients with acute heart failure. Int J Cardiol 370:229-235, 2023
• Mori H, Sumitomo N, Tsutsui K, Fukunaga H, Hayashi H, Nakajima H, Muraji S, Nabeshima T, Kawano D, Ikeda Y, Asano S, Nitta J, Watanabe S, Hokosaki T, Sato S, Chisaka T, Higaki T, Nakajima T, Tamura S, Kaneko Y, Ikeda K, Okada A, Kobayashi H, Motoki H, Minamiguchi H, Imamura T, Shizuta S, Kawamura M, Munetsugu Y, Suzuki T, Murakami T, Horigome H, Wada T, Takamuro M, Ozawa J, Suzuki H, Izumi D, Otsuki S, Chinushi M, Kato K, Miura M, Maeda J, Fukunaga M, Kondo H, Takahashi N, Tobiume T, Morishima I, Kuraishi K, Nakamura K, Hayashi H, Suzuki H, Yoshida Y, Fukamizu S, Hojo R, Nuruki N, Yoshinaga M, Hayashi K, Fukaya H, Kishihara J, Kobayashi T, Kato R. Efficacy of SubcutAneous implantable cardioVErter-defibrillators in ≤ 18 year-old CHILDREN: SAVE-CHILDREN Registry. Int J Cardiol 371:204-210, 2023
• Ozasa N, Kato T, Morimoto T, Yaku H, Yamamoto E, Inuzuka Y, Tamaki Y, Kitai T, Washida K, Seko Y, Yoshikawa Y, Sato Y, Motoki H, Kuwahara K, Kimura T. Polypharmacy and Clinical Outcomes in Hospitalized Patients With Acute Decompensated Heart Failure. J Cardiovasc Nurs 38(1):33-43, 2023
• Temma T, Lux RL, Yoshie K, Hayase J, Bradfield JS, Shivkumar K, Ajijola OA. The Derivative Tissue Activation as a Unique Marker of Arrhythmogenic Myocardium. Heart Rhythm 20(2):261-271, 2023
• Washida K, Kato T, Ozasa N, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Seko Y, Yamamoto E, Yoshikawa Y, Shiba M, Kitai T, Yamashita Y, Taniguchi R, Iguchi M, Nagao K, Kawase Y, Nishimoto Y, Kuragaichi T, Hotta K, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T. A comparison between hospital follow-up and collaborative follow-up in patients with acute heart failure. ESC Heart Fail 10(1):353-365, 2023
• Räber L, Ueki Y. Effects of PCSK9 inhibitors on platelet function. Euro Intervention 18:1215-1217, 2023
• Komatsu T, Miura T, Nomoto F, Itagaki T, Sunohara D, Mochidome T, Kasai T, Ikeda U. Successful treatment of recurrent superior vena cava syndrome due to pulmonary adenocarcinoma using intravascular ultrasound. J Cardiol Cases 27(2):76-79, 2023
• Kato T, Ueki Y, Minamisawa M, Miura T, Oyama Y, Hashizume N, Yokota D, Taki M, Senda K, Okina Y, Wakabayashi T, Fujimori K, Karube K, Sakai T, Nomi H, Yui H, Kanzaki Y, Machida K, Maruyama S, Nagae A, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K on behalf of I-PAD investigators. Association between complete revascularization of the coronary artery and clinical outcomes in peripheral artery disease: a sub‑analysis of the I‑PAD Nagano registry. Heart Vessels 38(8):1001-1008, 2023
• Okada A, Higuchi S, Shoda M, Tabata H, Kataoka S, Shoin W, Kobayashi H, Okano T, Yoshie K, Kato K, Saigusa T, Ebisawa S, Motoki H, Kuwahara K. Utility of a multi-purpose catheter for transvenous extraction of old broken leads: A novel technique for fragile leads. Heart Rhythm 20(7):976-981, 2023
• Ebisawa S, Tanaka H, Muramatsu T, Kishi K, Oikawa Y, Muto M, Okada H, Kawasaki T, Yoshikawa R, Hamazaki Y, Tsuchikane E. Impact of minimum contrast media volumes during percutaneous coronary intervention for chronic total occlusion lesion. Heart Vessels 38(9):1108-1116, 2023
• Aida K, Nagao K, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inada T, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Ozasa N, Kimura T. Prognostic value of the severity of clinical congestion in patients hospitalized for decompensated heart failure: Findings from the Japanese KCHF registry. J Card Fail 29(8):1150-1162, 2023
• Bär S, Kavaliauskaite R, Otsuka T, Ueki Y, Häner JD, Siontis GCM, Stortecky S, Shibutani H, Temperli F, Kaiser C, Iglesias JF, Jan van Geuns R, Daemen J, Spirk D, Engstrøm T, Lang I, Windecker S, Koskinas KC, Losdat S, Räber L on behalf of the PACMAN-AMI Investigators. Impact of alirocumab on plaque regression and haemodynamics of non-culprit arteries in patients with acute myocardial infarction: a prespecified substudy of the PACMAN-AMI trial. EuroIntervention 19(4):e286-e296, 2023
• Okumura Y, Nagashima K, Watanabe R, Yokoyama K, Kato T, Fukaya H, Hayashi H, Nakahara S, Shimizu W, Iwasaki YK, Fujimoto Y, Mukai Y, Ejima K, Otsuka T, Suzuki S, Murakami M, Kimura M, Harada M, Koyama J, Okamatsu H, Yamane T, Yamashita S, Tokuda M, Narui R, Takami M, Shoda M, Harada T, Nakajima I, Fujiu K, Hiroshima K, Tanimoto K, Fujino T, Nakamura K, Kumagai K, Okada A, Kobayashi H, Hayashi T, Watari Y, Hatsuno M, Tachibana E, Iso K, Sonoda K, Aizawa Y, Chikata A, Sakagami S, Inoue M, Minamiguchi H, Makino N, Satomi K, Yazaki Y, Aoyagi H, Ichikawa M, Haruta H, Hiro T, Okubo K, Arima K, Tojo T, Kihara H, Miyanaga S, Fukuda Y, Oiwa K, Fujiishi T, Akabane M, Ishikawa N, Kusano K, Miyamoto K, Tabuchi H, Shiozawa T, Miyamoto K, Mase H, Murotani K; REHEALTH AF study. Registry for Evaluating Healthy Life Expectancy and Long-Term Outcomes after Catheter Ablation of Atrial Fibrillation in the Very Elderly (REHEALTH AF) study: rationale and design of a prospective, multicentre, observational, comparative study. BMJ Open 13(2):e068894, 2023
• Hamatani Y, Kato T, Morimoto T, Iguchi M, Yaku H, Inuzuka Y, Kitai T, Nagao K, Tamaki Y, Yamamoto E, Ozasa N, Yamashita Y, Abe M, Sato Y, Kuwahara K, Akao M, Kimura T; KCHF Registry investigators. Association of intravenous heparin administration with in-hospital clinical outcomes among hospitalized patients with acute heart failure. Int J Cardiol 370:229-235, 2023
• Sunohara D, Miura T, Nomoto F, Itagaki T, Komatsu T, Mochidome T, Kasai T, IkedaU. Effectiveness of endovascular therapy using stents in a patient with celiac artery compression syndrome due to the median arcuate ligament: A case report. J Cardiol Cases 28(3):128-131, 2023
• Kanai M, Minamisawa M, Motoki H, Seko Y, Kimura K, Okano T, Ueki Y, Yoshie K, Kato T, Saigusa T, Ebisawa S, Okada A, Ozasa N, Kato T, Kuwahara K. Prognostic Impact of Hyperpolypharmacy Due to Noncardiovascular Medications in Patients After Acute Decompensated Heart Failure – Insights From the Clue of Risk Stratification in the ElderlyPatients With Heart Failure (CURE-HF) Registry -. Circ J PMID: 37544741 DOI: 10.1253/circj.CJ-22-0712
• Suzuki S, Murai K, Kataoka Y, Noguchi T. Proximal optimization technique with an ultra-short balloon as a bailout strategy for stent protrusion into the left main trunk. Cardiovasc Revasc Med PMID: 35941067 DOI: 10.1016/j.carrev.2022.07.023
• Machida K, Minamisawa M, Motoki H, Teramoto K, Okuma Y, Kanai M, Kimura K, Okano T, Ueki Y, Yoshie K, Kato T, Saigusa T, Ebisawa S, Okada A, Kuwahara K. Clinical Profile and Prognosis of Dementia in Patients With Acute Decompensated Heart Failure – From the CURE-HF Registry -. Circ J PMID: 37438112 DOI: 10.1253/circj.CJ-23-0129
• Itagaki T, Ebisawa S, Kato T, Miura T, Oyama Y, Hashizume N, Yokota D, Taki M, Senda K, Okina Y, Wakabayashi T, Fujimori K, Karube K, Sakai T, Nomoto F, Takamatsu T, Tanaka K, Mochidome T, Saigusa T, Motoki H, Kasai T, Ikeda U, Kuwahara K. Validation and Comparison of the Prognosis Predicting Ability of Inflammation-Based Scores Following Endovascular Treatment for Peripheral Artery Disease. Angiology PMID: 36882389 DOI: 10.1177/00033197231161394
• Ueki Y, Häner J, Losdat S, Gargiulo G, Shibutani H, Bär S, Otsuka T, Kavaliauskaite R, Mitter V, Temperli F, Spirk D, Stortecky S, Siontis G, Valgimigli M, Windecker S, Gutmann C, Koskinas KC, Mayr M, Raber L. Effect of Alirocumab Added to High-Intensity Statin on Platelet Reactivity and Non-coding RNAs in AMI Patients: A Substudy of the PACMAN-AMI Trial. Thromb Haemost　　　　PMID: 37595625 DOI: 10.1055/a-2156-7872

• Okano T, Okada A, Shoda M, Kuwahara K. Gigantic Pacemaker Pocket Abscess Infected by Staphylococcus epidermidis. Intern Med 61(4):593-594, 2022
• Suzuki S, Asano R, Aoki T, Nakayama S, Ueda J, Tsuji A, Noguchi T, Oga T. Prognostic impact of follow-up pulmonary vascular resistance in pulmonary arterial hypertension. Open Heart 9:e002054, 2022
• Nakamura C, Ebisawa S, Miura T, Nomi H, Kanzaki Y, Yui H, Maruyama S, Nagae A, Ueki Y, Sakai T, Kato T, Saigusa T, Okada A, Motoki H, Kuwahara K. Effects of cardiac surgical support on long‑term outcomes of emergent or complex percutaneous coronary intervention cases: a sub‑analysis of the SHINANO 5‑year registry. Heart Vessels 37(7):1106-1114, 2022
• Sakai T, Motoki H, Fuchida A, Takeuchi T, Otagiri K, Kanai M, Kimura K, Minamisawa M, Yoshie K, Saigusa T, Ebisawa S, Okada A, Kitabayashi H, Kuwahara K. Comparison of prognostic impact of anticoagulants in heart failure patients with atrial fibrillation and renal dysfunction: direct oral anticoagulants versus vitamin K antagonists. Heart Vessels 37(7):1232-1241, 2022
• Kato T, Fuke M, Nagai F, Nomi H, Kanzaki Y, Yui H, Maruyama S, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Successful endovascular treatment with a stent graft for chronic deep vein thrombosis with multiple arteriovenous fstulas: a case report. J Med Case Rep16(1):257, 2022
• Miura T, Miyashita Y, Hozawa K, Doijiri T, Kato T, Hayakawa N, Hashizume N, Nakano M, Ikeda U, Kuwahara K, on behalf of the ZERO Investigators. Cilostazol effectiveness in reducing drugcoated stent restenosis in the superficial femoral artery: The ZERO study. PLoS ONE 17(7):e0270992, 2022
• Tabata H, Okada A, Kobayashi H, Shoin W, Okano T, Higuchi S, Yagishita D, Ebisawa S, Motoki H, Shoda M, Kuwahara K. Usefulness of the controlled-rotation dilator sheath “Evolution RL” for extraction of old leads in two Japanese centers – An experience in use. J Cardiol 80(4):339-343, 2022
• Sakai T, Motoki H, Suzuki S, Fuchida A, Takeuchi T, Otagiri K, Kanai M, Kimura K, Minamisawa M, Yoshie K, Saigusa T, Ebisawa S, Okada A, Kitabayashi H, Kuwahara K. Gender diference in heart failure with preserved ejection fraction:clinical profles, examinations, and prognosis. Heart Vessels 37(10):1710-1718, 2022
• Nagae A, Ebisawa S, Saigusa T, Nishikawa K, Fujimori K, Yui H, Maruyama S, Nakamura C, Kashiwagi D, Kobayashi H, Sakai T, Senda K, Kato T, Miura T, Okada A, Motoki H, Kuwahara K. The Impact of Hyperuricemia on Patients With Low Body Mass Index After Endovascular Treatments: Data From the I-PAD Registry. Angiology 73(8):753-763, 2022
• Kato T, Miura T, Yamamoto S, Miyashita Y, Hashizume N, Shoin K, Sasaki S, Kanzaki Y, Yui H, Maruyama S, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Ikeda U, Kuwahara K; REASON Investigators. Intensive exercise therapy for restenosis after superficial femoral artery stenting: the REASON randomized clinical trial. Heart Vessels 37(9):1596-1603, 2022
• Ueki Y, Kuramitsu S, Saigusa T, Senda K, Matsuo H, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Tsujita K, Masamura K, Doijiri T, Sakai Y, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Kanemura N, Sonoda S, Yokoi H, Tanaka N, on behalf pf the J-CONFIRM Investigators. Long-Term Outcomes in Elderly Patients After Deferral of Coronary Revascularization Guided by Fractional Flow Reserve. Circ J 86(9):1329-1336, 2022
• Nishikawa K, Ebisawa S, Miura T, Kato T, Kanzaki Y, Abe N, Yokota D, Yanagisawa T, Senda K, Wakabayashi T, Oyama Y, Karube K, Itagaki T, Yui H, Maruyama S, Nagae A, Sakai T, Okina Y, Nakazawa S, Tsukada S, Saigusa T, Okada A, Motoki H, Kagoshima M, Kuwahara K. Impact of Frailty and Age on Clinical Outcomes in Patients Who Underwent Endovascular Therapy. J Endovasc Ther 29(6):845-854, 2022
• Komatsu T, Miura T, Sunohara D, Yahikozawa K, Momose T, Kouno T, Motoki H, Mochidome T, Kasai T, Kuwahara K, Ikeda U. Impact of Flood Due to Typhoon Hagibis on Cardiovascular and Cerebrovascular Events in the Disaster Area of Nagano City: A Sub-Analysis Using Data From the SAVE Trial. Disaster Med Public Health Prep 17:e113, 2022
• Yamazaki K, Miura T, Sunohara D, Komatsu T, Mochidome T, Kasai T, Ikeda U, Kuwahara K. Infective endocarditis caused by Streptococcus pneumoniae from sinusitis: A case report. J Cardiol Cases 25(5):279-281, 2022
• Ishii M, Kuramitsu S, Yamanaga K, Matsuo H, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Saigusa T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Masamura K, Doijiri T, Toyota F, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Kanemura N, Sonoda S, Yokoi H, Tanaka N, Tsujita K; J- CONFIRM Registry Investigators. Association of guideline-directed medical therapy adherence with outcomes after fractional flow reserve-based deferral of revascularization. Eur Heart J Cardiovasc Pharmacother 8(6):600-608, 2022
• Shiono Y, Kuramitsu S, Matsuo H, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Saigusa T, Sakamoto T, Suematsu N, Asano T, Tsujita K, Masamura K, Doijiri T, Toyota F, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Sonoda S, Tanaka A, Yokoi H, Tanaka N; J-CONFIRM Registry Investigators. Thrombotic Risk and Cardiovascular Events in Patients With Revascularization Deferral After Fractional Flow Reserve Assessment. JACC Cardiovasc Interv 5(4):427-439, 2022
• Kuramitsu S, Matsuo H, Shinozaki T, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Saigusa T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Tsujita K, Masamura K, Doijiri T, Toyota F, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Sonoda S, Yokoi H, Tanaka N; J-CONFIRM Investigators. Five-Year Outcomes After Fractional Flow Reserve-Based Deferral of Revascularization in Chronic Coronary Syndrome: Final Results From the J-CONFIRM Registry. Circ Cardiovasc Interv 15(2):e011387, 2022
• Inciardi RM, Claggett B, Minamisawa M, Shin SH, Selvaraj S, Goncalves A, Wang W, Kitzman D, Matsushita K, Prasad NG, Su J, Skali H, Shah AM, Chen LY, Solomon SD. Association of Left Atrial Structure and Function With Heart Failure in Older Adults. J Am Coll Cardiol 79(16)1549-1561, 2022
• Tsunekawa K, Kato T, Ebisawa S, Tsuzuki S, Takashimizu I, Yuzuriha S. Which plantar region can predict peripheral arterial disease by using laser speckleflowgraphy? Heart Vessels 37(5):738-744, 2022
• Inazumi H, Kuwahara K, Nakagawa Y, Kuwabara Y, Numaga-Tomita T, Kashihara T, Nakada T, Kurebayashi N, Oya M, Nonaka M, Sugihara M, Kinoshita H, Moriuchi K, Yanagisawa H, Nishikimi T, Motoki H, Yamada M, Morimoto S, Otsu K, Mortensen RM, Nakao K, Kimura T. NRSF-GNAO1 Pathway Contributes to the Regulation of Cardiac Ca2+ Homeostasis. Circ Res 130(2):234-248, 2022
• Seko Y, Kishimori T, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Coronary angiography in patients with acute heart failure: from the KCHF registry. ESC Heart Fail 9(1):531-544, 2022
• Seko Y, Yamamoto E, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Insomnia in patients with acute heart failure: from the KCHF registry. ESC Heart Fail 9(5):2988-2996, 2022
• Shiba M, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Nakagawa Y, Kuwahara K, Kimura T. Changes in BNP levels from discharge to 6-month visit predict subsequent outcomes in patients with acute heart failure. PLoS One 17(1):e0263165, 2022
• Shiba M, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T. Left atrial reverse remodeling improves risk stratification in patients with heart failure with recovered ejection fraction. Sci Rep 12(1):4473, 2022
• Nagao K, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inada T, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Ozasa N, Kimura T. Current use of inotropes according to initial blood pressure and peripheral perfusion in the treatment of congestive heart failure: findings from a multicentre observational study. BMJ Open 12(1):e053254, 2022
• Ogo T, Shimokawahara H, Kinoshita H, Sakao S, Abe K, Matoba S, Motoki H, Takama N, Ako J, Ikeda Y, Joho S, Maki H, Saeki T, Sugano T, Tsujino I, Yoshioka K, Shiota N, Tanaka S, Yamamoto C, Tanabe N, Tatsumi K; Study Group. Selexipag for the treatment of chronic thromboembolic pulmonary hypertension. Eur Respir J 60(1):2101694, 2022
• Ohuchi H, Kawata M, Uemura H, Akagi T, Yao A, Senzaki H, Kasahara S, Ichikawa H, Motoki H, Syoda M, Sugiyama H, Tsutsui H, Inai K, Suzuki T, Sakamoto K, Tatebe S, Ishizu T, Shiina Y, Tateno S, Miyazaki A, Toh N, Sakamoto I, Izumi C, Mizuno Y, Kato A, Sagawa K, Ochiai R, Ichida F, Kimura T, Matsuda H, Niwa K; Japanese Circulation Society Joint Working Group. JCS 2022 Guideline on Management and Re-Interventional Therapy in Patients With Congenital Heart Disease Long-Term After Initial Repair. Circ J 86(10):1591-1690, 2022
• Davies DR, Redfield MM, Scott CG, Minamisawa M, Grogan M, Dispenzieri A, Chareonthaitawee P, Shah AM, Shah SJ, Wehbe RM, Solomon SD, Reddy YNV, Borlaug BA, AbouEzzeddine OF. A Simple Score to Identify Increased Risk of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction. JAMA Cardiol 7(10):1036-1044, 2022
• Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, Kato Y, Numaga-Tomita T, Kaneko T, Mangmool S, Kuroda T, Okubo R, Sanbo M, Hirabayashi M, Sato Y, Nakagawa Y, Kuwahara K, Nagata R, Iribe G, Mori Y, Nishida M. Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through β-adrenoceptors. Nat Commun 13(1):6374, 2022

Inazumi H, Kuwahara K. NRSF/REST-Mediated Epigenomic Regulation in the Heart: Transcriptional Control of Natriuretic Peptides and Beyond. Biology (Basel) 11(8):1197, 2022

• Yamamoto E, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Seko Y, Shiba M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kimura T. Appetite loss at discharge from acute decompensated heart failure: Observation from KCHF registry. PLoS One 17(5):e0267327, 2022
• Nishimoto Y, Kato T, Morimoto T, Taniguchi R, Yaku H, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Kuwahara K, Ozasa N, Sato Y, Kimura T. Public assistance in patients with acute heart failure: a report from the KCHF registry. ESC Heart Fail 9(3):1920-1930, 2022
• Shimizu Y, Kondo K, Hayashida R, Sasaki KI, Ohtsuka M, Fukumoto Y, Takashima S, Inoue O, Usui S, Takamura M, Sakuma M, Inoue T, Nagata T, Akashi YJ, Yamada Y, Kato T, Kuwahara K, Tateno K, Kobayashi Y, Shibata R, Murohara T; TACT-ADRC multicenter trial Group. Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial. Angiogenesis 25(4):535-546, 2022
• Seko Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Starting Neurohormonal Antagonists in Patients With Acute Heart Failure With Mid-Range and Preserved Ejection Fraction. Circ J 86(10):1547-1558, 2022
• Watanabe M, Aonuma K, Murohara T, Okumura Y, Morimoto T, Okada S, Nakamura S, Uemura S, Kuwahara K, Takayama T, Doi N, Nakajima T, Horii M, Ishigami K, Nomoto K, Abe D, Oiwa K, Tanaka K, Koyama T, Sato A, Ueda T, Soeda T, Saito Y; PREVENT CINC-J Investigators. Prevention of Contrast-Induced Nephropathy After Cardiovascular Catheterization and Intervention With High-Dose Strong Statin Therapy in Japan – The PREVENT CINC-J Study. Circ J 86(9):1455-1463, 2022
• Yao A, Inuzuka R, Mizuno A, Iwano H, Tatebe S, Tsukamoto Y, Sakamoto I, Watanabe H, Fukuda N, Takechi F, Adachi S, Akazawa Y, Kuwahara K, Dohi K, Ishizu T, Miyake M, Koitabashi N, Hasegawa-Tamba S, Sato S, Fujii T, Ehara E, Minamino T, Yamada H, Yamashita E, Kawamatsu N, Masuda K, Soma K, Shiraishi I, Nagai R, Niwa K; JNCVD-ACHD investigators. Status of adult outpatients with congenital heart disease in Japan: The Japanese Network of Cardiovascular Departments for Adult Congenital Heart Disease Registry. J Cardiol 80(6):525-531, 2022

• Okada A, Shoda M, Tabata H, Kobayashi H, Shoin W, Okano T, Yoshie K, Kato K, Motoki H, Kuwahara K. Simultaneous infection of abandoned leads and newly implanted leadless cardiac pacemaker: Why did this occur? J Cardiol Cases 23(1):35-37, 2021
• Maruyama S, Ebisawa S, Miura T, Yui H, Kashiwagi D, Nagae A, Sakai T, Kato T, Saigusa T, Okada A, Motoki H, Kuwahara K. Impact of nutritional index on long‑term outcomes of elderly patients with coronary artery disease: sub‑analysis of the SHINANO 5 year registry. Heart Vessels 36(1):7-13, 2021
• Kinoshita H, Aoki T, Motoki H, Wakita T, Onishi Y, Watanabe-Fujinuma E, Kuwahara K. Patient Journey and Disease-Related Burden in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension: A Mixed Methods Study. Value Health Reg Issues 24(C):17-23, 2021
• Tabata H, Okada A, Kobayashi H, Shoin W, Okano T, Yoshie K, Motoki H, Shoda M, Kuwahara K. “Alpha”-Looped Broken Pacemaker Lead Inside the Heart. Circ J 85(1):77, 2021
• Kobayashi H, Tabata H, Shoin W, Okano T, Yoshie K, Okada A, Shoda M, Kuwahara K. A case of transient ventricular pre-excitation associated with takotsubo cardiomyopathy. J Electrocardiol 65:73-75, 2021
• Kashiwagi D, Ebisawa S, Yui H, Maruyama S, Nagae A, Sakai T, Kato T, Saigusa T, Okada A, Motoki H, Kuwahara K. Prognostic usefulness of residual SYNTAX score combined with clinical factors for patients with acute coronary syndrome who underwent percutaneous coronary intervention from the SHINANO Registry. Heart Vessels 36(2):170-179, 2021
• Okada A, Kato K, Shoda M, Tabata H, Yoshie K, Kuwahara K. Successful catheter ablation of atrial tachycardia in cor triatriatum sinister: A figure of eight reentry in the left atrial membrane. HeartRhythm Case Rep 7(2):109-111, 2021
• Nomoto F, Suzuki S, Hashizume N, Kanzaki Y, Maruyama T, Kozuka A, Saigusa T, Ebisawa S, Okada A, Motoki H, Yahikozawa K, Kuwahara K. A case of Dressler’s syndrome successfully treated with colchicine and acetaminophen. J Cardiol Cases 23(3):131-135, 2021
• Okada A, Tabata H, Shoda M, Shoin W, Kobayashi H, Okano T, Yoshie K, Kato K, Saigusa T, Ebisawa S, Motoki H, Kuwahara K. Safe and effective transvenous lead extraction for elderly patients utilizing non-laser and laser tools: A single-center experience in Japan. Heart Vessels 36(6):882-889, 2021
• Kuwahara K. The natriuretic peptide system in heart failure: Diagnostic and therapeutic implications. Pharmacol Ther 227:107863, 2021
• Harada M, Motoki H, Sakai T, Kuwahara K. Granulocyte colony stimulating factor-associated aortitis evaluated via multiple imaging modalities including vascular echography:a case report. Eur Heart J Case Rep 5(2): ytaa503, 2021
• Otagiri K, Machida K, Itagaki T, Takeuchi T, Tsujinaka Y, Yui H, Nakamura C, Sakai T, Kato T, Saigusa T, Ebisawa S, Motoki H, Kuwahara K, Kitabayashi H. Predictive Value of Abdominal Fat Distribution on Coronary Artery Disease Severity Stratified by Computed Tomography-Derived SYNTAX Score. Am J Cardiol 150:32-39, 2021
• Uchida M, Kashima Y, Mochizuki K, Sakamoto H, Mori K, Ebisawa S, Takeshige K, Nitta K, Kuwahara K, Imamura H. Multisystem Inflammatory Syndrome in Children – A New Syndrome Complicated With Acute Heart Failure Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectio. Circ J 85(6):948-952, 2021
• Higuchi S, Okada A, Shoda M, Yagishita D, Saito S, Kanai M, Kataoka S,Yazaki K, Tabata H, Kobayashi H, Shoin W, Okano T, Yoshie K, Ejima K, Kuwahara K, Hagiwara N. Leadless cardiac pacemaker implantations after infected pacemaker system removals in octogenarians. J Geriatr Cardiol 18(7):505-513, 2021
• Fuchida A, Suzuki S, Motoki H, Kanzaki Y, Maruyama T, Hashizume N, Kozuka A, Yahikozawa K, Kuwahara K. Prognostic significance of diastolic blood pressure in patients with heart failure with preserved ejection fraction. Heart Vessels 36(8):1159-1165, 2021
• Yoshie K, Okada A, Shoda M, Kuwahara K. Unique Atrial Tachycardia From the Right Inferior Pulmonary Vein Mimicking Multiple Focal Patterns in the Bilateral Atria and Aorta. Circ Rep 3(8):472-473, 2021
• Ebisawa S. Prediction and assessment of the long-term outcomes of coronary chronic total occlusion-percutaneous coronary intervention. Interv Cardiol 13 S5:103-108, 2021
• Kobayashi H, Ichimura H, Ohashi N, Shiba Y. Transplantation of Pluripotent Stem Cell-Derived Cardiomyocytes into a Myocardial Infarction Model of Cynomolgus Monkey. Methods Mol Biol 2320:295-302, 2021
• Shiba M, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T. Serum cholinesterase as a prognostic biomarker for acute heart failure. Eur Heart J Acute Cardiovasc Care 10(3):335-342, 2021
• Taki M, Miura T, Okina Y, Mochidome T, Kobayashi T, Kasai T, Ikeda U, Ezawa N, Sekijima Y, Kuwahara K. Searching for the Frequency of Cardiac Transthyretin Amyloidosis among Elderly Heart Failure Patients Noninvasively Using 99mTc-labeled Pyrophosphate Scintigraphy. Shinshu Med J 69(1):37-44, 2021
• Imanishi A, Ichise H, Fan C, Nakagawa Y, Kuwahara K, Sumiyama K, Matsuda M, Terai K. Visualization of Spatially-Controlled Vasospasm by Sympathetic Nerve-Mediated ROCK Activation. Am J Pathol 191(1):194-203, 2021
• Shiba M, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Prognostic value of reduction in left atrial size during a follow-up of heart failure: an observational study. BMJ Open 11(2):e044409, 2021
• Senda K, Miura T, Kato T, Kanzaki Y, Abe N, Yokota D, Yanagisawa T, Okina Y, Wakabayashi T, Oyama Y, Karube K, Itagaki T, Yoda H, Shoin K, Oguchi Y, Aizawa K, Suzuki C, Kuwahara K; on behalf of the I-PAD NAGANO registry investigators. Association of the Prognosis of Ankle-brachial Index Improvement One Year Following Endovascular Therapy in Patients with Peripheral Artery Disease: Data from the I-PAD NAGANO Registry. Intern Med 60(13):1999-2006, 2021
• Wakabayashi S, Joshita S, Kimura K, Motoki H, Kobayashi H, Yamashita Y, Sugiura A, Yamazaki T, Kuwahara K, Umemura T. Protocol: Prospective observational study investigating the prevalence and clinical outcome of portopulmonary hypertension in Japanese patients with chronic liver disease. PLoS One 16(4):e0249435, 2021
• Itagaki T, Motoki H, Otagiri K, Machida K, Takeuchi T, Kanai M, Kimura K, Higuchi S, Minamisawa M, Kitabayashi H, Kuwahara K. Inflammation-based assessment for the risk stratification of mortality in patients with heart failure. Sci Rep 11(1):14989, 2021
• Seko Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. A decrease in tricuspid regurgitation pressure gradient associates with favorable outcome in patients with heart failure. ESC Heart Fail 8:2826-2836, 2021
• Kawase Y, Kato T, Morimoto T, Hata R, Murai R, Tada T, Katoh H, Kadota K, Yamamoto E, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Yoshikawa Y, Iguchi M, Nagao K, Sato Y, Kuwahara K, Kimura T. Admission systolic blood pressure as a prognostic predictor of acute decompensated heart failure: A report from the KCHF registry. PLoS One 16(7):e0253999, 2021
• Tamaki Y, Yaku H, Morimoto T, Inuzuka Y, Ozasa N, Yamamoto E, Yoshikawa Y, Miyake M, Kondo H, Tamura T, Kitai T, Iguchi M, Nagao K, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Toyofuku M, Sato Y, Kuwahara K, Nakagawa Y, Kato T, Kimura T; KCHF Study Investigators. Lower In-Hospital Mortality With Beta-Blocker Use at Admission in Patients With Acute Decompensated Heart Failure. J Am Heart Assoc 10(13):e020012, 2021
• Okina Y, Miura T, Senda K, Taki M, Kobayashi M, Kanai M, Okuma Y, Yanagisawa T, Hashizume N, Otagiri K, Shoin K, Watanabe N, Ebisawa S, Karube K, Nakajima H, Saigusa T, Miyashita Y, Kashiwagi D, Machida K, Abe N, Tachibana T, Kanzaki Y, Maruyama T, Nomi H, Sakai T, Yui H, Mochidome T, Kobayashi T, Kasai T, Ikeda U, Kuwahara K. Prognostic ability of mid-term worsening renal function after percutaneous coronary intervention: findings from the SHINANO registry. Heart Vessels 36(10): 1496-1505, 2021
• Kobayashi H, Okada A, Tabata H, Shoin W, Okano T, Yoshie K, Oguchi Y, Kato K, Motoki H, Shoda M, Kuwahara K. Association between Inter-atrial Septum motion and Persistent Atrial Fibrillation Recurrence after Catheter Ablation. Shinshu Med J 69(4):189-201, 2021
• Kato T, Nagae A, Sakai T, Saigusa T, Ebisawa S, Kuwahara K. Successful bailout of stent graft stuck in stent occlusion lesion. Cardiovasc Interv Ther 36(4):535-536, 2021
• Miura T, Ueki Y, Senda K, Otagiri K, Tachibana T, Saigusa T, Ebisawa S, Motoki H, Ikeda U, Kuwahara K. Early vascular response of ultra‑thin bioresorbable polymer sirolimus‑eluting stents assessed by optical frequency domain imaging: the EVALUATION study. Cardiovasc Interv Ther 36(3):281-288, 2021
• Fujimori K, Okada A, Tabata H, Shoda M, Kuwahara K. Percutaneous removal of a displaced inferior vena cava filter using a loop-wire technique and lead-extraction sheaths. Circ J 85(8):1403, 2021
• Minamisawa M, Inciardi RM, Claggett B, Cuddy SAM, Quarta CC, Shah AM, Dorbala S, Falk RH, Matsushita K, Kitzman DW, Chen LY, Solomon SD. Left atrial structure and function of the amyloidogenic V122I transthyretin variant in elderly African Americans. Eur J Heart Fail 23(8):1290-1295, 2021
• Sunohara D, Miura T, Komatsu T, Hashizume N, Momose T, Kono T, Motoki H, Mochidome T, Kasai T, Kuwahara K, Ikeda U. Relationship between the flood disaster caused by the Reiwa first year east Japan typhoon and cardiovascular and cerebrovascular events in Nagano City: The SAVE trial. J Cardiol 78(5): 447-455, 2021
• Yoshie K, Yamasaki M, Yokoyama M, Ueki Y, Tachibana E, Yonemoto N, Nagao K. Prognostic beneits of prior amiodarone or β-blocker use before the onset of ventricular arrhythmia with hemodynamic collapse. Heart Vessels 36(9):1430-1437, 2021
• Yanagisawa S, Takahashi Y, Sasaki J, Takasone K, Yoshie K, Koyama J, Katoh N, Yazaki M, Kuwahara K, Fujinaga Y, Sekijima Y. Absolute quantitative analysis of cardiac amyloidosis using SPECT/CT with (99m)Tc-pyrophosphate. Amyloid 28(3):213-214, 2021
• Itagaki T, Ebisawa S, Otagiri K, Kato T, Miura T, Kanzaki Y, Abe N, Yokota D, Yanagisawa T, Senda K, Okina Y, Wakabayashi T, Oyama Y, Karube K, Machida K, Takeuchi T, Saigusa T, Motoki H, Kitabayashi H, Kuwahara K. Body composition and mortality in patients undergoing endovascular treatment for peripheral artery disease. Heart Vessels 36(12):1830-1840, 2021
• Minamisawa M, Claggett B, Suzuki K, Hegde SM, Shah AM, Desai AS, Lewis EF, Shah SJ, Sweitzer NK, Fang JC, Anand IS, O’Meara E, Rouleau JL, Pitt B, Pfeffer MA, Solomon SD, Vardeny O. Association of Hyper-Polypharmacy With Clinical Outcomes in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail 14(11):e008293, 2021
• Iguchi M, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T, Hamatani Y, Yamashita Y, Masunaga N, Ogawa H, Ishii M, An Y, Taniguchi R, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Seko Y, Toyofuku M, Furukawa Y, Ando K, Kadota K, Abe M, Akao M, Sato Y, Kuwahara K, Kimura T. Ischemic Stroke in Acute Decompensated Heart Failure: From the KCHF Registry. J Am Heart Assoc 10(21):e022525, 2021
• Seko Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Jinnai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Newly Diagnosed Infection After Admission for Acute Heart Failure: From the KCHF Registry. J Am Heart Assoc 10(22):e023256, 2021
• Seko Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Improved and new-onset anemia during follow-up in patients with acute decompensated heart failure: Characteristics and outcomes. Medicine (Baltimore) 100(32):e26892, 2021
• Washida K, Kato T, Ozasa N, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T. Risk Factors and Clinical Outcomes of Nonhome Discharge in Patients With Acute Decompensated Heart Failure: An Observational Study. J Am Heart Assoc 10(15):e020292, 2021
• Suzuki K, Claggett B, Minamisawa M, Nochioka K, Mitchell GF, Anand IS, Zannad F, Shah SJ, Lefkowitz M, Shi V, Pfeffer MA, McMurray JJV, Solomon SD. Pulse Pressure, Prognosis, and Influence of Sacubitril/Valsartan in Heart Failure With Preserved Ejection Fraction. Hypertension 77(2):546-556, 2021
• Biering-Sørensen T, Minamisawa M, Liu J, Claggett B, Papolos AI, Felker GM, McMurray JJV, Legg JC, Malik FI, Honarpour N, Kurtz CE, Teerlink JR, Solomon SD. The effect of the cardiac myosin activator, omecamtiv mecarbil, on right ventricular structure and function in chronic systolic heart failure (COSMIC-HF). Eur J Heart Fail 23(6):1052-1056, 2021

• Okada A, Shoin W, Shoda M, Tabata H, Kobayashi H, Okano T, Yoshie K, Kato K, Kuwahara K. Defibrillation failure with short ICD charge time: Internal short circuit of a Durata lead. J Cardiol Cases 21(2):59-62, 2020
• Yoshie K, Rajendran PS, Massoud L, Mistry J, Swid MA, Wu X, Sallam T, Zhang R, Goldhaber JI, Salavatian S, Ajijola OA. Cardiac TRPV1-afferent signaling promotes arrhythmogenic ventricular remodeling after myocardial infarction. JCI Insight 5(3):e124477, 2020
• Tabata H, Okada A, Kobayashi H, Shoin W, Okano T, Yoshie K, Motoki H, Shoda M, Kuwahara K. Successful hot balloon ablation for focal atrial tachycardia derived from the left superior pulmonary vein antrum. J Arrhythm 36(2):368-370, 2020
• Kato T, Miyashita Y, Sone H, Mizukami T, Kanno Y, Oguchi T, Yokota D, Shiotsuki N, Mizukami E, Terashima M, Aruga M, Yui H, Maruyama S, Kobayashi H, Kashiwagi D, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Impact of Ambulation Status in Patients with End-stage Renal Disease on Hemodialysis due to Diabetic Nephropathy: The PREDICT Study. Shinshu Med J 68(3):131-138, 2020
• Shoin W, Ebisawa S, Saigusa T, Sakai T, Oguchi Y, Okada A, Motoki H, Kuwahara K. Prognostic Impact of Cardio-renal-anemia Syndrome in Patients at Risk for Heart Failure from the IMPACT-ABI study. Shinshu Med J 68(3):139-147, 2020
• Suzuki S, Motoki H, Kanzaki Y, Maruyama T, Hashizume N, Kozuka A, Yahikozawa K, Kuwahara K. Prognostic significance of resting heart rate in atriak fibrillation patients with heart failure with reduced ejection fraction. Heart Vessels 35(8):1109-1115, 2020
• Suzuki S, Motoki H, Kanzaki Y, Maruyama T, Hashizume N, Kozuka A, Yohikozawa K, Kuwahara K. A Predictive Model for 6-Month Mortality in Elderly Patients with Heart Failure. Int Heart J 61(2):325-331, 2020
• Suzuki S, Motoki H, Kanzaki Y, Maruyama T, Hashizume N, Kozuka A, Yahikozawa K, Kuwahara K. Prognostic impact of mineralocorticoid receptor antagonist in patients with heart failure with preserved ejection fraction. ESC Heart Fail 7(5):2752-2761, 2020
• Motoki H, Masuda I, Yasuno S, Oba K, Shoin W, Usami S, Saito Y, Waki M, Komatsu M, Ueshima K, Nakagawa Y, Son C, Yonemitsu S, Hiramitsu S, Konda M, Onishi K, Kuwahara K. Rationale and design of the EMPYREAN study. ESC Heart Fail 7(5):3134-3141, 2020
• Yui H, Ebisawa S, Miura T, Nakamura C, Maruyama S, Kashiwagi D, Nagae A, Sakai T, Kato T, Saigusa T, Okada A, Motoki H, Kuwahara K. Impact of changes in body mass index after percutaneous coronary intervention on long-term outcomes in patients with coronary artery disease. Heart Vessels 35(12):1657-1663, 2020
• Ebisawa S, Kohsaka S, Muramatsu T, Kashima Y, Okamura A, Yamane M, Sakurada M, Matsuno S, Kijima M, Habara M. Derivation and validation of the J-CTO extension score for pre-procedural prediction of major adverse cardiac and cerebrovascular events in patients with chronic total occlusions. PLOS ONE 15(9):e0238640, 2020
• Okano T, Motoki H, Minamisawa M, Kimura K, Kanai M, Yoshie K, Higuchi S, Saigusa T, Ebisawa S, Okada A, Shoda M, Kuwahara K. Cardio-renal and cardio-hepatic interactions predict cardiovascular events in elderly patients with heart failure. PLOS ONE 15(10):e0241003, 2020
• Ichimura H, Kadota S, Kashihara T, Yamada M, Ito K, Kobayashi H, Tanaka Y, Shiba N, Chuma S,Tohyama S, Seto T, Okada K, Kuwahara K, Shiba Y. Increasing predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo. Sci Rep 10(1):11883, 2020
• Nakagawa Y, Kuwahara K. Sodium-Glucose Cotransporter-2 inhibitors are potential therapeutic agents for treatment of non-diabetic heart failure patients. J Cardiol 76(2):123-131, 2020
• Takeuchi T, Yui H, Yui C, Itagaki T, Machida K, Tsujinaka Y, Fujimori A, Takahashi K, Otagiri K, Nakajima Y, Kasuga W, Kondoh S, Kitabayashi H. Reimplantation of a Pacemaker into a Subpectoral Pocket Via the Lateral Approach in Collaboration with Plastic Surgeons. Intern Med 59(7): 967-970, 2020
• Utsunomiya M, Takahara M, Iida O, Soga Y, Hata Y, Shiraki T, Nagae A, Kato T, Kobayashi N, Suematsu N, Tasaki J, Horie K, Uchida D, Kodama A, Azuma N, Nakamura M. Limb-Based Patency After Surgical vs Endovascular Revascularization in Patients with Chronic Limb-Threatening Ischemia. J Endovasc Ther. 27(4):584-594, 2020
• Endo J, Sano M, Izumiya Y, Tsujita K, Nakamura K, Tahara N, Kuwahara K, Inomata T, Ueda M, Sekijima Y, Ando Y, Tsutsui H, Isobe M, Fukuda K. A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis. Circ J 84(1):15-17, 2020
• Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Ozasa N, Kimura T. Association With Controlling Nutritional Status (CONUT) Score and In-hospital Mortality and Infection in Acute Heart Failure. Sci Rep 10(1):3320, 2020
• Yaku H, Kato T, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T, Kato M, Ikeda T, Furukawa Y, Nakagawa Y, Sato Y, Kuwahara K, Kimura T. Risk Factors and Clinical Outcomes of Functional Decline During Hospitalisation in Very Old Patients With Acute Decompensated Heart Failure: An Observational Study. BMJ Open 10(2):e032674, 2020
• Shoji K, Yanishi K, Shiraishi H, Yamabata S, Yukawa A, Teramukai S, Imai K, Ito-Ihara T, Tao M, Higashi Y, Ishigami T, Fukumoto Y, Kuwahara K, Matoba S. Establishment of Optimal Exercise Therapy Using Near-Infrared Spectroscopy Monitoring of Tissue Muscle Oxygenation After Therapeutic Angiogenesis for Patients With Critical Limb Ischemia: A Multicenter, Randomized, Controlled Trial. Contemp Clin Trials Commun 17:100542, 2020
• Ito S, Hashimoto Y, Majima R, Nakao E, Aoki H, Nishihara M, Ohno-Urabe S, Furusho A, Hirakata S, Nishida N, Hayashi M, Kuwahara K, Fukumoto Y. MRTF-A Promotes Angiotensin II-induced Inflammatory Response and Aortic Dissection in Mice. PLoS One 15(3):e0229888, 2020
• Seko Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T. Association between body mass index and prognosis of patients hospitalized with heart failure. Sci Rep 10(1):16663, 2020
• Yamamoto E, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Himura Y, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Seko Y, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Sex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry. ESC Heart Fail 7(5):2485-2493, 2020
• Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Seko Y, Shiba M, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T. Association of an increase in serum albumin levels with positive 1-year outcomes in acute decompensated heart failure: A cohort study. PLoS One 15(12): e0243818, 2020
• Yoshikawa Y, Tamaki Y, Morimoto T, Yaku H, Yamamoto E, Inuzuka Y, Ozasa N, Kitai T, Nagao K, Sato Y, Kondo H, Tamura T, Nakagawa Y, Kuwahara K, Kato T, Kimura T. Impact of left ventricular ejection fraction on the effect of renin-angiotensin system blockers after an episode of acute heart failure: From the KCHF Registry. PLoS One 15(9):e0239100, 2020
• Nishimoto Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Kuwahara K, Ozasa N, Sato Y, Kimura T. C-reactive protein at discharge and 1-year mortality in hospitalised patients with acute decompensated heart failure: an observational study. BMJ Open 10(12):e041068, 2020
• Shimizu Y, Kondo K, Fukumoto Y, Takamura M, Inoue T, Nagata T, Akashi YJ, Yamada Y, Kuwahara K, Kobayashi Y, Shibata R, Murohara T; TACT-ADRC Multicenter Trial Group. Rationale and Design of Therapeutic Angiogenesis by Cell Transplantation Using Adipose-Derived Regenerative Cells in Patients With Critical Limb Ischemia – TACT-ADRC Multicenter Trial. Circ Rep 2(9):531-535, 2020

• Minamisawa M, Koyama J, Ikeda U. Left ventricular noncompaction cardiomyopathy: Recent update on genetics, usefulness of biomarkers, and speckle imaging. J Cardiol 73(1):95-96, 2019
• Kozuka A, Koyama J, Sekijima Y, Ikeda U. Quantitative Analysis of Endocardial and Epicardial Left Ventricular Myocardial Deformation in Patients with Cardiac Amyloidosis. Shinshu Med J 67(1):49-62, 2019
• Oguchi Y, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Ankle-Brachial Index as a Prognostic Indicator in Patients with Atrial Fibrillation Patients – A Subanalysis of the IMPACT-ABI Study. Shinshu Med J 67(3):197-204, 2019
• Motoki H, Yasukochi S, Takigiku K, Takei K, Okamura T, Kimura K, Minamisawa M, Okada A, Saigusa T, Ebisawa S, Seto T, Shoda M, Okada K, Kuwahara K. Establishment of a Healthcare System for Patients with Adult Congenital Heart Disease in Collaboration with Children’s Hospitals: The Nagano Model. Circ J 83(2):424-431, 2019
• Motoki H, Nishimura M, Kanai M, Kimura K, Minamisawa M, Yamamoto S, Saigusa T, Ebisawa S, Okada A, Kuwahara K. Impact of inpatient cardiac rehabilitation on Barthel Index score and prognosis in patients with acute decompensated heart failure. Int J Cardiol 293:125-130, 2019
• Tabata H, Motoki H, Sakai T, Okada A, Kuwahara K. Epicardial Stone: Unfamiliar Calcified Mass at the Site of a Left Ventricular Old Myocardial Infarction. Circ J 83(9):262
• Nakagawa Y, Nishikimi T, Kuwahara K. Atrial and brain natriuretic peptides: Hormones secreted from the heart. Peptides 111:18-25, 2019
• Komatsu T, Motoki H, Kimura K, Saigusa T, Ebisawa S, Yokokawa Y, Ando H, Ichino T, Kuwahara K. A case of thrombolytic therapy with recombinant tissue plasminogen activator for mechanical valve thrombosis at 9 weeks of pregnancy in a Japanese woman. J Cardiol Cases 19(1):15-18, 2019
• Okano T, Okada A, Tabata H, Kobayashi H, Shoin W, Yoshie K, Oguchi Y, Shoda M, Kuwahara K. Wire perforation causing cardiopulmonary arrest during radiofrequency hot balloon ablation for pulmonary vein isolation. J Cardiol Cases 19(5):169-172, 2019
• Kobayashi H, Okada A, Tabata H, Shoin W, Okano T, Yoshie K, Oguchi Y, Kato K, Shoda M, Kuwahara K. Association between reactive hyperemia peripheral arterial tonometry index and atrial fibrillation recurrence after catheter ablation. Int J Cardiol Heart Vasc 24:100385, 2019
• Ejima K, Kato K, Okada A, Wakisaka O, Kimura R, Ishizawa M, Imai T, Toyama Y, Shoda M, Hagiwara N. Comparison between Contact Force Monitoring and Unipolar Signal Modification as a Guide for Catheter Ablation of Atrial Fibrillation: A Prospective Multi-Center Randomized . Circ Arrhythm Electrophysiol 12(8):e007311, 2019
• Shoji K, Yanishi K, Yoshimi R, Hamada N, Kondo K, Fujimoto K, Nakajima H, Kuwahara K, Higashi Y, Fukumoto Y, Murohara T, Matoba S; TACT Follow up Study Investigators. Impact of Therapeutic Angiogenesis Using Autologous Bone Marrow-Derived Mononuclear Cells Implantation in Critical Limb Ischemia With Scleroderma – Subanalysis of the Long-Term Clinical Outcomes Survey. Circ J 83(3):662-671, 2019
• Oshita K, Kozasa Y, Nakagawa Y, Kuwabara Y, Kuwahara K, Nakagawa T, Nakashima N, Hiraki T, Takano M. Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia. J Physiol Sci 69(4):653-660, 2019
• Yoshikawa Y, Shiomi H, Kuwahara K, Sowa N, Yaku H, Yamashita Y, Tazaki J, Imai M, Kato T, Saito N, Shizuta S, Ono K, Kimura T. Utility of copeptin for predicting long-term clinical outcomes inpatients with heart failure. J Cardiol 73(5):379-385, 2019
• Yaku H, Kato T, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Seko Y, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators. Association of Mineralocorticoid Receptor Antagonist Use With All-Cause Mortality and Hospital Readmission in Older Adults With Acute Decompensated Heart Failure. JAMA Netw Open 2(6):e195892, 2019
• Suzuki S, Motoki H, Minamisawa M, Okuma Y, Shoin W, Okano T, Kimura K, Ebisawa S, Okada A, Kuwahara K. Prognostic significance of high‑sensitivity cardiac troponin in patients with heart failure with preserved ejection fraction. Heart Vessels 34(10):1650-1656, 2019
• Itagaki T, Okada A, Tabata H, Shoin W, Kobayashi H, Okano T, Oguti Y, Mochidome T, Saigusa T, Ebisawa S, Motoki H, Shoda M, Kuwahara K. Successful inferior vena cava filter removal using pacemaker lead extraction methods. J Cardiol Cases 19(4):129-132, 2019
• An J, Naruse TK, Hinohara K, Soejima Y, Sawabe M, Nakagawa Y, Kuwahara K, Kimura A. MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages. J Mol Cell Cardiol 133:26-35, 2019
• Koyama J, Minamisawa M, Sekijima Y, Kuwahara K, Katsuyama T, Maruyama K. Role of echocardiography in assessing cardiac amyloidosis : a systematic review. J Echocardiogr 17(2):64-75, 2019
• Minamisawa M, Claggett B, Adams D, Kristen AV, Merlini G, Slama MS, Dispenzieri A, Shah AM, Falk RH, Karsten V, Sweetser MT, Chen J, Riese R, Vest J, Solomon SD. Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis The APOLLO Study. JAMA Cardiol 4(5):466-472, 2019
• Ueki Y, Miura T, Mochidome T, Senda K, Ebisawa S, Saigusa T, Motoki H, Okada A, Koyama J, Kuwahara K. Comparison of leg loader and treadmill exercise for evaluating patients with peripheral artery disease. Heart Vessels 34(4):590-596, 2019
• Ueki Y, Mohri M, Matoba T, Kadokami T, Suwa S, Yagi T, Takahashi H, Tanaka N, Hokama Y, Fukuhara R, Onitsuka K, Tachibana E, Yonemoto N, Nagao K; Japanese Circulation Society Shock Registry Scientific Committee. Prognostic Value of Neurological Status on Hospital Arrival for Short-Term Outcome in Patients With Cardiovascular Shock – Sub-analysis of the Japanese Circulation Society Cardiovascular Shock Registry. Circ J 83(6):1247-1253, 2019
• Minamisawa M, Seidelmann SB, Claggett B, Hegde SM, Shah AM, Desai AS, Lewis EF, Shah SJ, Sweitzer NK, Fang JC, Anand IS, O’Meara E, Rouleau JL, Pitt B, Solomon SD. Impact of Malnutrition Using Geriatric Nutritional Risk Index in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail 7(8):664-675, 2019

• Okada A, Shoda M, Tabata H, Shoin W, Kobayashi H, Okano T, Yoshie K, Oguchi Y, Takeuchi T, Kato K, Kuwahara K. Single-center experience with percutaneous lead extraction of cardiac implantable electric devices. J Cardiol 71(2):192-196, 2018
• Ebisawa S, Ueki Y, Mochidome T, Senda K, Nishimura H, Saigusa T, Miura T, Motoki H, Koyama J, Ikeda U. Comparison of platelet aggregation response in switching regimen from prasugrel to clopidogrel between CYP2C19 extensive versus non‑extensive metabolizers. Cardiovasc Interv Ther 33(3):277-284, 2018
• Senda K, Miura T, Minamisawa M, Ueki Y, Mochidome T, Nomi H, Shoin W, Higuchi S, Oguchi Y, Nishimura H, Saigusa T, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U, Kuwahara K. Predictive Value of Underweight Status for Patients with Peripheral Artery Disease with Claudication. Angiology 69(6):513-522, 2018
• Minamisawa M, Miura T, Motoki H, Ueki Y, Nishimura H, Shimizu K, Shoin W, Harada M, Mochidome T, Senda K, Yoshie K, Oguchi Y, Hashizume N, Abe N, Saigusa T, Ebisawa S, Izawa A, Koyama J, Ikeda U, Kuwahara K. Geriatric Nutritional Risk Index Predicts Cardiovascular Events in Patients at Risk for Heart Failure. Circ J 82(6):1614-1622, 2018
• Taki M, Miura T, Kobayashi T, Kasai T, Maruyama T, Hayakawa M, Matsumura Y, Yamaki F, Ikeda U. Primary External Iliac Venous Aneurysm: A Case Report. Ann Vasc Dis 11(1):143-147, 2018
• Nakagawa Y, Nishikimi T, Sakai H, Ohno S, Kinoshita H, Inazumi H, Moriuchi K, Kuwahara K, Horie M, Kimura T. Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report. Clin Biochem 52:148-152, 2018
• Fujii T, Hirota K, Yasoda A, Takizawa A, Morozumi N, Nakamura R, Yotsumoto T, Kondo E, Yamashita Y, Sakane Y, Kanai Y, Ueda Y, Yamauchi I, Yamanaka S, Nakao K, Kuwahara K, Jindo T, Furuya M, Mashimo T, Inagaki N, Serikawa T, Nakao K. Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death. PLoS One 13(3):e0194812, 2018
• Miura T, Miyashita Y, Soga Y, Hozawa K, Doijiri T, Ikeda U, Kuwahara K on behalf of the DEBATE in SFA investigators. Drug-Eluting Versus Bare-Metal Stent Implantation with or without Cilostazol in the Treatment of the Superficial Femoral Artery. Circ Cardiovasc Interv 11(8):e006564, 2018
• Kuwahara K, Nakagawa Y, Nishikimi T. Cutting Edge of Brain Natriuretic Peptide (BNP) Research – The Diversity of BNP Immunoreactivity and Its Clinical Relevance. Circ J 82(10):2455-2461, 2018
• Harada M, Motoki H, Kashima Y, Nakamura C, Hashizume N, Kishida D, Imamura H, Kuwahara K. T-wave alternans in a case with systemic lupus erythematosus-related myocarditis. J Cardiol Cases 18(4):119-122, 2018
• Minamisawa M, Koyama J, Kozuka A, Miura T, Saigusa T, Ebisawa S, Motoki H, Okada A, Ikeda U, Kuwahara K. Duration of myocardial early systolic lengthening for diagnosis of coronary artery disease. Open Heart 5:e000896, 2018
• Yamamoto S, Ishida T, Misawa K, Ohira M, Yajima F, Higuchi S, Yamasaki S, Yoshimura Y. The simple method for predicting metabolic equivalents using heart rate in patients with cardiovascular disease. Int J Cardiol Heart Vasc 19:88-89, 2018
• Yaku H, Ozasa N, Morimoto T, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Sasaki K, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kato T, Kimura T, on behalf of the KCHF Study Investigators. Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan – Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry. Circ J 82(11):2811-2819, 2018
• Nishimura A, Shimauchi T, Tanaka T, Shimoda K, Toyama T, Kitajima N, Ishikawa T, Shindo N, Numaga-Tomita T, Yasuda S, Sato Y, Kuwahara K, Kumagai Y, Akaike T, Ide T, Ojida A, Mori Y, Nishida M. Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence. Sci Signal 2018 Nov 13;11(556): eaat5185
• Kuwabara J, Kuwahara K, Kuwabara Y, Yasuno S, Nakagawa Y, Ueshima K, Kimura T. Cross-sectional study of the association between day-to-day home blood pressure variability and visceral fat area measured using the dual impedance method. PLoS One. 13(11):e0206945, 2018
• Imamura H, Kamijo H, Nitta K, Okada A. Nocturnal enuresis as the initial symptom of life-threatening arrhythmia: a case report. BJGP Open 2018 Dec12; 2(4): bjgpopen18X101624
• Fischer K, Yamaji K, Luescher S, Ueki Y, Jung B, von Tengg-Kobligk H, Windecker S, Friedrich MG, Eberle B, Guensch DP. Feasibility of cardiovascular magnetic resonance to detect oxygenation deficits in patients with multi-vessel coronary artery disease triggered by breathing maneuvers. J Cardiovasc Magn Reson 20(1):31, 2018
• Windecker S, Piccolo R, Ueki Y. Long-Term Assessment of Bioresorbable Coronary Scaffolds: Disappearing Stents, Reappearing Atherosclerosis. J Am Coll Cardiol 71(17):1894-1896, 2018
• Yoshie K, Rajendran PS, Massoud L, Kwon O, Tadimeti V, Salavatian S, Ardell JL, Shivkumar K, Ajijola OA. Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress. Am J Physiol Heart Circ Physiol 314(5):H954-H966, 2018
• Yoshie K, Ajijola OA. Managing ventricular arrhythmias after failed catheter ablation: Interrupting the reentrant loop of repeat ablation. Heart Rhythm 15(1):63-64, 2018
• Yoshie K, Ajijola OA. Overview of Electrophysiological and Echocardiographic Findings and Outcomes with His Bundle Pacing for Cardiac Resynchronization. Current Cardiovascular Risk Reports 12:15, 2018

• Harada M, Izawa A, Hidaka H, Nakanishi K, Terasawa F, Motoki H, Yazaki Y, Ikeda U, Hongo M, on behalf of the Study Project on Prevention of Metabolic Syndrome among Children, Adolescents, and Young Adults in Shinshu. Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students. J Cardiol 69(1):222-227, 2017
• Harada M, Miura T, Kobayashi T, Kobayashi H, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Hashizume N, Ebisawa S, Miyashita Y, Ikeda U, On behalf of the SHINANO registry investigators. Clinical impact of complete revascularization in elderly patients with multi-vessel coronary artery disease undergoing percutaneous coronary intervention: A sub-analysis of the SHINANO registry. Int J Cardiol 230:413-419, 2017
• Takeuchi T, Yazaki Y, Okada A, Shimizu K, Shoin W, Harada M, Minamisawa M, Yoshie K, Oguchi Y, Motoki H, Koshikawa M, Kasai H, Izawa A, Koyama J, Shoda M, Ikeda U. Failure of steroid withdrawal guided by 18F-FDG PET in a patient with cardiac sarcoidosis. J Cardiol Cases 15(1):10-13, 2017
• Suzuki K, Mizutani Y, Soga Y, Iida O, Kawasaki D, Yamauchi Y, Hirano K, Koshida R, Kamoi D, Tazaki J, Higashitani M, Shintani Y, Yamaoka T, Okazaki S, Suematsu N, Tsuchiya T, Miyashita Y, Shinozaki N, Takahashi H, Inoue N. Efficacy and Safety of Endovascular Therapy for Aortoiliac TASC D Lesions. Angiology 68(1):67-73, 2017
• Ueki Y, Izawa A, Kashiwagi D, Nishiyama S, Aso S, Suzuki C, Sakurai S, Oguchi K, Yazaki Y, Ikeda U, Kuwahara K. Diagnostic advantage of stress computed tomography myocardial perfusion over single-photon emission computed tomography for the assessment of myocardial ischemia. J Cardiol 70(2):147-154, 2017
• Ueki Y, Miura T, Minamisawa M, Abe N, Nishimura H, Hashizume N, Mochidome T, Harada M, Shimizu K, Oguchi Y, Yoshie K, Shoin W, Ebisawa S, Motoki H, Koyama J, Ikeda U. The usefulness of brachial‑ankle pulse wave velocity in predicting long‑term cardiovascular events in younger patients. Heart Vessels 32(6):660-667, 2017
• Miura T, Miyashita Y, Motoki H, Kobayashi H, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eizawa T, Aso S, Uchikawa S, Hashizume N, Senda K, Morita T, Ebisawa S, Izawa A, Koyama J, Ikeda U. Comparison of mid-term outcomes between patients with and without atrial fibrillation undergoing coronary stenting in the second-generation drug-eluting stent era: from the SHINANO registry. Cardiovasc Interv Ther 32(3):206-215, 2017
• Minamisawa M, Miura T, Motoki H, Kobayashi H, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Uchikawa S, Senda K, Morita T, Hashizume N, Abe N, Ebisawa S, Izawa A, Miyashita Y, Koyama J, Ikeda U;SHINANO Registry Investigators. Prediction of 1-year clinical outcomes using the SYNTAX score in patients with prior heart failure undergoing percutaneous coronary intervention: sub-analysis of the SHINANO Registry. Heart Vessels 32(4):399-407, 2017
• Nishimura H, Miura T, Minamisawa M, Ueki Y, Abe N, Hashizume N, Mochidome T, Harada M, Shimizu K, Shoin W, Yoshie K, Oguchi Y, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U. Prognostic value of ankle brachial index for future incident heart failure in patients without previous heart failure: data from the impressive predictive value of ankle brachial index for clinical long term outcome in patients with cardiovascular disease examined by ABI study. Heart Vessels 32(3):295-302, 2017
• Miura T, Miyashita Y, Motoki H, Kobayashi H, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Hashizume N, Ebisawa S, Ikeda U. Efficacy and Safety of Percutaneous Coronary Intervention for Elderly Patients in the Second-Generation Drug-Eluting Stent Era: The SHINANO Registry. Angiology 68(8):688-697, 2017
• Ueki Y, Miura T, Miyashita Y, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U. Inflammatory Cytokine Levels After Endovascular Therapy in Patients with Peripheral Artery Disease. Angiology 68(8):734-740, 2017
• Ueki Y, Miura T, Miyashita Y, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U. Reply: Inflammatory Cytokine Levels After Endovascular Therapy in Patients With Peripheral Artery Disease. Angiology 68(8):742, 2017
• Minamisawa M, Miura T, Motoki H, Ueki Y, Shimizu K, Shoin W, Harada M, Mochidome T, Yoshie K, Oguchi Y, Hashizume N, Nishimura H, Abe N, Ebisawa S, Izawa A, Koyama J, Ikeda U. Prognostic Impact of Diastolic Wall Strain in Patients at Risk for Heart Failure. Int Heart J 58(2):250-256, 2017
• Abe N, Miura T, Miyashita Y, Hashizume N, Ebisawa S, Motoki H, Tsujimura T, Ishihara T, Uematsu M, Katagiri T, Ishihara R, Tosaka A, Ikeda U. Long-term prognostic implications of the admission shock index in patients with acute myocardial infarction who received percutaneous coronary intervention. Angiology 68(4):339-345, 2017
• Nishimura H, Miura T, Minamisawa M, Ueki Y, Abe N, Hashizume N, Mochidome T, Harada M, Shimizu K, Shoin W, Yoshie K, Oguchi Y, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U, Kuwahara K. Ankle-brachial index for the prognosis of cardiovascular disease in patients with mild renal insufficiency. Intern Med 56(16):2103-2111, 2017
• Yoshinaga T, Yazaki M, Ohno M, Kodama S, Koyama J, Sekijima Y. Cardiac Amyloidosis Associated With Amyloidogenic Transthyretin V122I Variant in an Elderly Japanese Woman. Circ J 81(6):893-894, 2017
• Okada A, Shoda M, Takeuchi T, Kato K, Shoin W, Okano T, Kobayashi H, Oguchi Y, Kuwahara K. Hot balloon ablation of persistent atrial fibrillation with a dilated left atrium in a case of dilated cardiomyopathy. International Journal of Diagnostic Imaging 4(2):28-30, 2017
• Okada A, Kashima Y, Tomita T, Takeuchi T, Oguchi Y, Yoshie K, Shoin W, Shoda M, Nitta K, Kuwahara K, Imamura H. Cardiac hyaluronan may be associated with the persistence of atrial fibrillation. Heart Vessels 32(9):1144-1150, 2017
• Ogasawara T, Okano S, Ichimura H, Kadota S, Tanaka Y, Minami I, Uesugi M, Wada Y, Saito N, Okada K, Kuwahara K, Shiba Y. Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model. Sci Rep 7(1):8630, 2017
• Miura T, Minamisawa M, Ueki Y, Abe N, Nishimura H, Hashizume N, Mochidome T, Harada M, Oguchi Y, Yoshie K, Shoin W, Saigusa T, Ebisawa S, Motoki H, Koyama J, Ikeda U, Kuwahara K. Impressive predictive value of ankle-brachial index for very long-term outcomes in patients with cardiovascular disease: IMPACT-ABI study. PLoS One 12(6):e0177609, 2017
• Nakagawa Y, Nishikimi T, Kuwahara K, Fujishima A, Oka S, Tsutamoto T, Kinoshita H, Nakao K, Cho K, Inazumi H, Okamoto H, Nishida M, Kato T, Fukushima H, Yamashita JK, Wijnen WJ, Creemers EE, Kangawa K, Minamino N, Nakao K, Kimura T. MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts. J Am Heart Assoc 6(2): e003601, 2017
• Nakao K, Kuwahara K, Nishikimi T, Nakagawa Y, Kinoshita H, Minami T, Kuwabara Y, Yamada C, Yamada Y, Tokudome T, Nagai-Okatani C, Minamino N, Nakao YM, Yasuno S, Ueshima K, Sone M, Kimura T, Kangawa K, Nakao K. Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity. Hypertension 69(2):286-296, 2017
• Tanabe N, Ikeda S, Tahara N, Fukuda K, Hatano M, Ito H, Nakayama T, Anzai T, Hashimoto A, Inoue T, Kajinami K, Kihara Y, Kinoshita H, Kuwahara K, Murohara T, Okazaki O, Sakai S, Satoh T, Takeda Y, Takeishi Y, Taniguchi M, Watanabe H, Yamamoto T, Yamauchi-Takihara K, Yoshioka K, Sasayama S. Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension. Circ J 81(9):1360-1367, 2017
• Harada E, Mizuno Y, Kugimiya F, Shono M, Maeda H, Yano N, Kuwahara K, Yasue H. B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction – Relevance to Age-Related Left Ventricular Modeling in Japanese -. Circ J 81(7):1006-1013, 2017
• Saigusa T, Matsuo H, Suzuki T. Angiographical Changes Induced by Tiny Coronary Fistula. Cardiovasc Imaging Asia 1(3):208-209, 2017
• Kanzaki Y, Miura T, Hashizume N, Saigusa T, Ebisawa S, Kuwahara K. Unique angiographic findings in a patient with myocardial ischemia and immunoglobulin G4-related disease. SAGE Open Medical Case Reports 5:1-4, 2017
• Hashizume N, Miura T, Miyashita Y, Motoki H, Ebisawa S, Izawa A, Koyama J, Ikeda U, Kuwahara K; SHINANO Registry Investigators. Prognostic Value of Ankle-Brachial Index in Patients Undergoing Percutaneous Coronary Intervention: In-Hospital and 1-Year Outcomes From the SHINANO Registry. Angiology 68(10):884-892, 2017

• Okada A, Kashima Y, Tomita T, Takeuchi T, Aizawa K, Takahashi M, Ikeda U. Characterization of cardiac oxidative stress levels in patients with atrial fibrillation. Heart Vessels 31(1):80-87, 2016
• Kimura K, Momose T, Hasegawa T, Morita T, Misawa T, Motoki H, Izawa A, Ikeda U. Early administration of tolvaptan preserves renal function in elderly patients with acute decompensated heart failure. J Cardiol 67(5):399-405, 2016
• Hioki H, Miura T, Miyashita Y, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U, on behalf of the SHINANO registry investigators. Circulating eicosapentaenoic acid to oleic acid ratio and risk for cardiovascular events in patients with coronary artery disease: A sub-analysis of the SHINANO registry. IJC Metabolic & Endocrine 10:1-6, 2016
• Ueki Y, Miura T, Miyashita Y, Motoki H, Shimada K, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Uchikawa S, Hashizume N, Sekimura N, Morita T, Ebisawa S, Izawa A, Koyama J, Ikeda U. Predictive Value of Combining the Ankle-Brachial Index and SYNTAX Score for the Prediction of Outcome after Percutaneous Coronary Intervention (From the SHINANO Registry). Am J Cardiol 117(2):179-185, 2016
• Hioki H, Miyashita Y, Shiraki T, Iida O, Uematsu M, Miura T, Ebisawa S, Ikeda U. Impact of deteriorated calcium- phosphate homeostasis on amputation- free survival after endovascular revascularization in patients with critical limb ischemia on hemodialysis. Vasc Med 21(2):137-143, 2016
• Hioki H, Motoki H, Izawa A, Kashima Y, Miura T, Ebisawa S, Tomita T, Miyashita Y, Koyama J, Ikeda U. Impact of oral beta-blocker therapy on mortality after primary percutaneous coronary intervention for Killip class 1 myocardial infarction. Heart Vessels 31(5):687-693, 2016
• Ebisawa S, Kurita T, Tanaka N, Nasu K, Kimura M, Ito T, Kinoshita Y, Tsuchikane E, Terashima M, Suzuki T. Impact of minimum contrast media volumes during elective percutaneous coronary intervention for prevention of contrast-induced nephropathy in patients with stable coronary artery disease. Cardiovasc Interv Ther 31(1):13-20, 2016
• Minamisawa M, Motoki H, Izawa A, Kashima Y, Hioki H, Abe N, Miura T, Ebisawa S, Miyashita Y, Koyama J, Ikeda U. Comparison of Inflammatory Biomarkers in Outpatients With Prior Myocardial Infarction. Int Heart J 57(1):11-17, 2016
• Minamisawa M, Koyama J, Kozuka A, Miura T, Ebisawa S, Motoki H, Okada A, Izawa A, Ikeda U. Regression of left ventricular hypertrabeculation is associated with improvement in systolic function and favorable prognosis in adult patients with non-ischemic cardiomyopathy. J Cardiol 68(5):431-438, 2016
• Minamisawa M, Koyama J, Ikeda U. Author’s reply. J Cardiol 68(4):359-360, 2016
• Minamisawa M, Koyama J, Sekijima Y, Ikeda S, Kozuka A, Ebisawa S, Miura T, Motoki H, Okada A, Izawa A, Ikeda U. Comparison of the standard and speckle tracking echocardiographic features of wild-type and mutated transthyretin cardiac amyloidoses. Eur Heart J Cardiovasc Imaging 17(4):402-410, 2016
• Ueki Y, Mohri M, Matoba T, Tsujita Y, Yamasaki M, Tachibana E, Yonemoto N, Nagao K. Characteristics and predictors of mortality in patients with cardiovascular shock in japan – Results From the Japanese Circulation Society Cardiovascular Shock Registry –. Circ J 80(4):852-859, 2016
• Hasegawa T, Tabata H, Kagoshima M, Okada H, Aida H, Shoin W, Shoin K, Ikada U. A case of pregnancy-associated acute myocardial infarction with refractory ventricular fibrillation and heart failure. J Cardiol Cases 14(1):13-16, 2016
• Nakagawa M, Sekijima Y, Yazaki M, Tojo K, Yoshinaga T, Doden T, Koyama J, Yanagisawa S, Ikeda S. Carpal tunnel syndrome: a common initial symptom of systemic wild-type ATTR (ATTRwt) amyloidosis. Amyloid 23(1):58-63, 2016
• Nakamura A, Fueki N, Shiba N, Motoki H, Miyazaki D, Nishizawa H, Echigoya Y, Yokota T, Aoki Y, Takeda S. Deletion of exons 3-9 encompassing a mutational hot spot in the DMD gene presents an asymptomatic phenotype, indicating a target region for multiexon skipping therapy. J Hum Genet 61(7):663-667, 2016
• Koyama J. Prognostic Significance of Occult Transthyretin Cardiac Amyloidosis in Patients With Severe Aortic Stenosis Undergoing Surgical Aortic Valve Replacement: An Unrecognized Disease Modifier. Circ Cardiovasc Imaging 9:e005320, 2016
• Shiba Y, Gomibuchi T, Seto T, Wada Y, Ichimura H, Tanaka Y, Ogasawara T, Okada K, Shiba N, Sakamoto K, Ido D, Shiina T, Ohkura M, Nakai J, Uno N, Kazuki Y, Oshimura M, Minami I, Ikeda U. Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts. Nature 538(7625):388-391, 2016
• Nishimura H, Miura T, Minamisawa M, Ueki Y, Abe N, Hashizume N, Mochidome T, Harada M, Shimizu K, Shoin W, Yoshie K, Oguchi Y, Ebisawa S, Motoki H, Izawa A, Koyama J, Ikeda U, Kuwahara K. Clinical Characteristics and Outcomes of Patients with High Ankle-Brachial Index from the IMPACT-ABI Study. PLoS One 11(11):e0167150, 2016
• Nakajima H, Yoshioka J, Totsuka N, Miyazawa I, Usui T, Urasawa N, Kobayashi T, Mochidome T. Activities of daily living as an additional predictor of complications and outcomes in elderly patients with acute myocardial infarction. Clin Interv Aging 11:1141-1147, 2016
• Numaga-Tomita T, Kitajima N, Kuroda T, Nishimura A, Miyano K, Yasuda S, Kuwahara K, Sato Y, Ide T, Birnbaumer L, Sumimoto H, Mori Y, Nishida M. TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis. Sci Rep 6:39383, 2016
• Tomita T, Higashikata T, Mawatari E, Tsunemi K, Sasaki H, Yoshie K, Oguchi Y, Takeuchi T, Okada A, Ikeda U. Impact of nocturnal oxygen therapy for central sleep apnea syndrome on nocturnal premature ventricular contractions. Interv Cardiol 8(1):587-590, 2016

■Shiba Y. New strategy for the treatment of myocarditis by cell-sheet technology. Circ J 79(1):51-52, 2015

■Izawa A, Kashima Y, Miura T, Ebisawa S, Kitabayashi H, Yamamoto H, Sakurai S, Kagoshima M, Tomita T, Miyashita Y, Koyama J, Ikeda U. Assessment of Lipophilic vs. Hydrophilic Statin Therapy in Acute Myocardial Infarction. Circ J 79(1):161-168, 2015

■Abe N, Kashima Y, Izawa A, Motoki H, Ebisawa S, Miyashita Y, Imamura H, Ikeda U.A 2-year follow-up of oxidative stress levels in patients with ST-segment elevation myocardial infarction: A subanalysis of the ALPS-AMI study. Angiology 66(3):271-277, 2015

■Takeuchi T, Tomita T, Yoshie K, Hioki H, Oguchi Y, Miura T, Ebisawa S, Motoki H, Okada A, Aizawa K, Izawa A, Miyashita Y, Koyama J, Ikeda U. Electrocardiographic J waves are associated with right ventricular morphology and function: evaluation by cardiac magnetic resonance imaging. Heart Vessels 30(1):98-107, 2015

■Hioki H, Miyashita Y, Miura T, Ebisawa S, Motoki H, Izawa A, Tomita T, Koyama J, Ikeda U. Prognostic improvement by multidisciplinary therapy in patients with critical limb ischemia. Angiology 66(2):187-194, 2015

■Takeuchi T, Tomita T, Kasai H, Kashiwagi D, Yoshie K, Yaguchi T, Oguchi Y, Kozuka A, Gautam M, Motoki H, Okada A, Shiba Y, Aizawa K, Izawa A, Miyashita Y, Koyama J, Hongo M, Ikeda U. A young patient with atypical type-B Wolff-Parkinson-White syndrome accompanied by left ventricular dysfunction. J Arrhythm 31(1):50-54, 2015

■Park JH, Kusunose K, Motoki H, Kwon DH, Grimm RA, Griffin BP, Marwick TH, Popović ZB. Assessment of Right Ventricular Longitudinal Strain in Patients with Ischemic Cardiomyopathy: Head-to-Head Comparison between Two-Dimensional Speckle-Based Strain and Velocity Vector Imaging Using Volumetric Assessment by Cardiac Magnetic Resonance as a “Gold Standard”. Echocardiography 32(6):956-965, 2015

■Ikeda U, Minamisawa M, Koyama J. Isolated left ventricular non- compaction cardiomyopathy in adults. J Cardiol 65(2):91-97, 2015

■Suematsu N, Iida O, Takahara M, Yamauchi Y, Soga Y, Nakano M, Hirano K, Kawasaki D, Yamaoka T, Suzuki K, Shintani Y, Miyashita Y, Tazaki J, Meno H, Inou T. Prognostic Factors in Hemodialysis Patients Undergoing Endovascular Treatment for Critical Limb Ischemia due to Isolated Below-the-Knee Disease. J Atheroscler Thromb 22(4):404-414, 2015

■Fujihara M, Yokoi Y, Abe T, Soga Y, Yamashita T, Miyashita Y, Nakamura M, Yokoi H, Ito S; J-RAS Study Investigators. Clinical outcome of renal artery stenting for hypertension and chronic kidney disease up to 12 months in the J-RAS Study. Circ J 79(2):351-359, 2015

■Okada A, Izawa A, Motoki H, Tomita T, Miyashita Y, Koyama J, Aizawa K, Shoda M, Ikeda U. Initial experience of percutaneous extraction of infected cardiac implantable electric devices using excimer laser. Shinshu Med J 63(2):103-108, 2015

■Gautam M, Fujita D, Kimura K, Ichikawa H, Izawa A, Hirose M, Kashihara T, Yamada M, Takahashi M, Ikeda U, Shiba Y. Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model. J Mol Cell Cardiol 81:139-149, 2015

■Koyama J, Ikeda S, Ikeda U. Echocardiographic assessment of the cardiac amyloidoses. Circ J 79(4):721-734, 2015

■Shiraki T, Iida O, Takahara M, Soga Y, Yamauchi Y, Hirano K, Kawasaki D, Fujihara M, Utsunomiya M, Tazaki J, Yamaoka T, Shintani Y, Suematsu N, Suzuki K, Miyashita Y, Tsuchiya T, Uematsu M. Predictors of Delayed Wound Healing after Endovascular Therapy of Isolated Infrapopliteal Lesions Underlying Critical Limb Ischemia in Patients with High Prevalence of Diabetes Mellitus and Hemodialysis. Eur J Vasc Endovasc Surg 49(5):565-573, 2015

■Yamasaki S, Izawa A, Koshikawa M, Saigusa T, Ebisawa S, Miura T, Shiba Y, Tomita T, Miyashita Y, Koyama J, Ikeda U. Association between estimated glomerular filtration rate and peripheral arterial disease. J Cardiol 66(5):430-434, 2015

■Hioki H, Miura T, Miyashita Y, Motoki H, Shimada K, Kobayashi M, Nakajima H, Kimura H, Mawatari E, Akanuma H, Sato T, Ebisawa S, Ikeda U. Risk stratification using the CHA2DS2-VASc score in patients with coronary heart disease undergoing percutaneous coronary intervention ; sub-analysis of SHINANO registry. IJC Heart & Vasculature 7:76-81, 2015

■Minamisawa M, Izawa A, Motoki H, Kashima Y, Hioki H, Abe N, Miura T, Ebisawa S, Miyashita Y, Koyama J, Ikeda U. Prognostic significance of neuroadrenergic dysfunction for cardiovascular events in patients with acute myocardial infarction. Circ J 79(10):2238-2245, 2015

■Miura T, Izawa A, Motoki H, Miyashita Y, Kashima Y, Ebisawa S, Tomita T, Koyama J, Ikeda U. Clinical Impact of Rapid Reduction of Low-Density Lipoprotein Cholesterol Level on Long-Term Outcome of Acute Myocardial Infarction in the Statin Era: Subanalysis of the ALPS-AMI Study. PLoS One 10(6):e0127835, 2015

■Ebisawa S, Izawa A, Ueki Y, Hioki H, Minamisawa M, Hashizume N, Abe N, Kashima Y, Miura T, Takeuchi T, Motoki H, Okada A, Miyashita Y, Koyama J, Ikeda U. Impact of combination therapy with statin and ezetimibe on secondary prevention for post-acute myocardial infarction patients in the statin era. IJC Heart & Vasculature 8: 154–160, 2015

■Koyama J, Minamisawa M, Sekijima Y, Ikeda S, Kozuka A, Ebisawa S, Miura T, Motoki H, Okada A, Izawa A, Ikeda U. Left ventricular deformation and torsion assessed by speckle-tracking echocardiography in patients with mutated transthyretin-associated cardiac amyloidosis and the effect of diflunisal on myocardial function. IJC Heart & Vasculature 9:1-10, 2015

■Hioki H, Miura T, Motoki H, Kobayashi H, Kobayashi M, Nakajima H, Kimura H, Mawatari E, Akanuma H, Sato T, Ebisawa S, Miyashita Y, Ikeda U, On behalf of the SHINANO registry investigators. Lean body mass index prognostic value for cardiovascular events in patients with coronary artery disease. Heart Asia 7(2): 12-18, 2015

■Okada A, Aizawa K, Tomita T, Yoshie K, Takeuchi T, Shoda M, Ikeda U. Successful transjugular extraction of a lead in front of the anterior scalene muscle by using snare technique. J Arrhythm 31(4): 249-251, 2015

■Okamoto S, Iida O, Nakamura M, Yamauchi Y, Fukunaga M, Yokoi Y, Soga Y, Zen K, Hirano K, Suematsu N, Suzuki K, Shintani Y, Miyashita Y, Urasawa K, Kitano I, Yamaoka T, Ohura N, Hamasaki T, Uematsu M, Nanto S; on behalf of the OLIVE Investigators. Postprocedural Skin Perfusion Pressure Correlates With Clinical Outcomes 1 Year After Endovascular Therapy for Patients With Critical Limb Ischemia. Angiology 66(9):862-866, 2015

■Iida O, Nakamura M, Yamauchi Y, Fukunaga M, Yokoi Y, Yokoi H, Soga Y, Zen K, Suematsu N, Inoue N, Suzuki K, Hirano K, Shintani Y, Miyashita Y, Urasawa K, Kitano I, Tsuchiya T, Kawamoto K, Yamaoka T, Uesugi M, Shinke T, Oba Y, Ohura N, Uematsu M, Takahara M, Hamasaki T, Nanto S; OLIVE Investigators. 3-Year Outcomes of the OLIVE Registry, a Prospective Multicenter Study of Patients With Critical Limb Ischemia: A Prospective, Multi-Center, Three-Year Follow-Up Study on Endovascular Treatment for Infra-Inguinal Vessel in Patients With Critical Limb Ischemia. JACC Cardiovasc Interv 8(11): 1493-1502, 2015

■Shiba N, Miyazaki D, Yoshizawa T, Fukushima K, Shiba Y, Inaba Y, Imamura M, Takeda S, Koike K, Nakamura A. Differential roles of MMP-9 in early and late stages of dystrophic muscles in a mouse model of Duchenne muscular dystrophy. Biochim Biophys Acta 1852: 2170-2182, 2015

■Miyashita Y, Ikeda U, Soga Y, Yokoi H, Suzuki K, Inoue N. Results of the retrospective analysis of renal artery stenting for the salvage of renal function study. Angiology 65(7):620-623, 2014

■Saigusa T, Izawa A, Miura T, Ebisawa S, Shiba Y, Miyashita Y, Tomita T, Koyama J, Fukui D, Takano T, Amano J, Ikeda U. Low levels of high-density lipoprotein cholesterol predict the presence of coronary artery disease in patients with aortic aneurysms. Angiology 65(8):710-715, 2014

■Gomi S, Nakata T, Kashiwabara T, Ikeda U, Yamada M. TRPM4 channels mediate hypertonicity-induced, Ca2+-impermeable, non-selective cation currents in a cervical cancer cell line, HeLa cells. Shinshu Med J 62(1):33-44, 2014

■Gautam M, Izawa A, Saigusa T, Yamasaki S, Motoki H, Tomita T, Miyashita Y, Koyama J, Hongo M, Ikeda U. The traditional japanese medicine (Kampo) boiogito has a dual benefit in cardiorenal syndrome: A pilot observational study. Shinshu Med J 62(2):89-97, 2014

■Aihara H, Soga Y, Iida O, Suzuki K, Tazaki J, Shintani Y, Miyashita Y; REAL-AI Registry Investigators. Long-Term Outcomes of Endovascular Therapy for Aortoiliac Bifurcation Lesions in the Real-AI Registry. J Endovasc Ther. 21(1):25-33, 2014

■Soga Y, Iida O, Suzuki K, Hirano K, Kawasaki D, Shintani Y, Suematsu N, Yamaoka T, Tsuchiya T, Miyashita Y, Okazaki S, Shinozaki N, Takahashi H. Clinical impact of bisoprolol versus carvedilol in patients undergoing femoropopliteal stenting. J Atheroscler Thromb 21(7):691-702, 2014

■Miura T, Miyashita Y, Motoki H, Shimada K, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Uchikawa S, Hashizume N, Sekimura N, Morita T, Ebisawa S, Izawa A, Tomita T, Koyama J, Ikeda U. In-hospital clinical outcomes of elderly patients (≥80 Years) undergoing percutaneous coronary intervention. Circ J 78(5):1097-1103, 2014

■Miura T, Soga Y, Miyashita Y, Iida O, Kawasaki D, Hirano K, Ikeda U. Five-year prognosis after endovascular therapy in claudicant patients with iliofemoral artery disease. J Endovasc Ther 21(3): 381-388, 2014

■Ueki Y, Izawa A, Ebisawa S, Motoki H, Miyashita Y, Tomita T, Koyama J, Takano T, Amano J, Ikeda U. Infective endocarditis associated with mitral valve prolapse in a patient with klinefelter syndrome. Intern Med 53(9):969-972, 2014

■Motoki H, Borowski AG, Shrestha K, Hu B, Kusunose K, Troughton RW, Tang WH, Klein AL. Right ventricular global longitudinal strain provides prognostic value incremental to left ventricular ejection fraction in patients with heart failure. J Am Soc Echocardiogr 27(7):726-732, 2014

■Ebisawa S, Kashima Y, Miyashita Y, Yamazaki S, Abe N, Saigusa T, Miura T, Motoki H, Izawa A, Ikeda U. Impact of endovascular therapy on oxidative stress in patients with peripheral artery disease. Circ J 78(6):1445-1450, 2014

■Motoki H, Koyama J, Izawa A, Tomita T, Miyashita Y, Takahashi M, Ikeda U. Impact of azelnidipine and amlodipine on left ventricular mass and longitudinal function in hypertensive patients with left ventricular hypertrophy. Echocardiography 31(10):1230-1238, 2014

■Iida O, Soga Y, Takahara M, Kawasaki D, Yamauchi Y, Suzuki K, Hirano K, Koshida R, Kamoi D, Tazaki J, Higashitani M, Shintani Y, Yamaoka T, Okazaki S, Suematsu N, Tsuchiya T, Miyashita Y, Shinozaki N, Takahashi H,Uematsu M. Perioperative complications after aorto-iliac stenting: associated factors and impact on follow-up cardiovascular prognosis. Eur J Vasc Endovasc Surg. 47(2):131-138, 2014

■Alraies MC, Kusunose K, Negishi K, Yarmohammadi H, Motoki H, AlJaroudi W, Popović ZB, Klein AL. Relation between echocardiographically estimated and invasively measured filling pressures in constrictive pericarditis. Am J Cardiol 113(11):1911-1916, 2014

■Hioki H, Miyashita Y, Miura T, Ebisawa S, Motoki H, Izawa A, Tomita T, Koyama J, Ikeda U. Diagonostic value of peripheral fractional flow reserve in isolated lliac artery stenosis : A comparison with the post-exercise ankle-brachial index. J Endovasc Ther 21(5):625-632, 2014

■Morita T, Izawa A, Hamano H, Asano N, Kozuka A, Moteki H, Fuke M, Koyama J, Amano J, Ikeda U. Significant pericardial involvement of immunoglobulin g4-related disease. Ann Thorac Surg. 98(2):e47-e49, 2014

■Gautam M, Izawa A, Shiba Y, Motoki H, Takeuchi T, Okada A, Tomita T, Miyashita Y, Koyama J, Ikeda U. Importance of fatty acid compositions in patients with peripheral arterial disease. PLoS One 9(9):e107003, 2014

■Yoshie K, Tomita T, Takeuchi T, Okada A, Miura T, Motoki H, Ikeda U. Renewed impact of lidocaine on refractory ventricular arrhythmias in the amiodarone era. Int J Cardiol 176(3):936-940, 2014

■Shiba Y, Filice D, Fernandes S, Minami E, Dupras SK, Biber BV, Trinh P, Hirota Y, Gold JD. Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct Model. J Cardiovasc Pharmacol Ther 19(4):368-381, 2014

■Motoki H, Negishi K, Kusunose K, Popović ZB, Bhargava M, Wazni OM, Saliba WI, Chung MK, Marwick TH, Klein AL. Global left atrial strain in the prediction of sinus rhythm maintenance after catheter ablation for atrial fibrillation. J Am Soc echocardiogr 27(11):1184-1192, 2014

■Lowe BS, Kusunose K, Motoki H, Varr B, Shrestha K, Whitman C, Tang WH, Thomas JD, Klein AL. Prognostic significance of left atrial appendage “Sludge” in patients with atrial fibrillation: A new transesophageal echocardiographic thromboembolic risk factor. J Am Soc echocardiogr 27(11):1176-1183, 2014

■Iida O, Takahara M, Soga Y, Yamauchi Y, Hirano K, Tazaki J, Yamaoka T, Suematsu N, Suzuki K, Shintani Y, Miyashita Y, Uematsu M. Impact of angiosome-oriented revascularization on clinical outcomes in critical limb ischemia patients without concurrent wound infection and diabetes. J Endovasc Ther 21(5):607-615, 2014

■Soga Y, Iida O, Takahaera M, Hirano K, Suzuki K, Kawasaki D, Miyashita Y, Tsuchiya T. Two-year life expectancy in patients with critical limb ischemia. JACC Cardiovasc Interv. 7(12):1444-1449, 2014

• Kato T, et al. Impact of HDL to major adverse limb event in end-stage renal disease on hemodialysis due to diabetic nephropathy. from PREDICT study. The Leipzig Interventional Course(LINC)2019. 2019.1.22-25；Germany(Leipzig)
• Sakai T, Kato T, Yui H, Maruyama S, Kasiwagi D, Nagae A, Senda K, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K, Miyashita Y, Miura T, Kanno H, Sone H, Tokoo M, Ako S, Mizukami E, Terashima M, Yokota D, Nakagawa M, Fujimori Y, Higuchi M. Non-Ambulatory State among Hemodialysis Patients is Associates with Mortality and Lower Limb Events: Insights from PREDICT Study. The Leipzig Interventional Course(LINC)2019. 2019.1.22-25；Germany(Leipzig)
• Nagae A, Nishikawa K, Miura T, Senda K, Taki M, Kobayashi T, Kanai M, Okuma Y, Yanagisawa T, Hashizume N, Otagiri K, Shoin K, Watanabe N, Karube K, Nakajima H, Miyashita Y, Fujimori K, Sunohara D, Yui H, Maruyama S, Nakamura C, Tabata H, Kashiwagi D, Kobayashi H, Sakai T, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. The Impact of Diabetes and Hba1c on Elder-Patients After Percutaneous Coronary Intervention: From Shinano Registry. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Okano T, Motoki H, Minamisawa M, Kimura K, Ebisawa S, Okada A, Shoda M, Kuwahara K. Prognostic Impact of Geriatric Nutritional Risk Index in Elderly Patients With Heart failure. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Kashiwagi D, Miura T, YUi H, Maruyama S, Nakamura C, Nagae A, Sakai T, Senda K, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Impact of the Clinical Syntax Score on 5-Year Clinical Outcomes After Percutaneous Coronary Intervention From SHINANO Registry. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Nakamura C, Ebisawa S, Miura T, Senda K, Taki M, Kobayashi M, Kanai M, Okuma Y, Yanagisawa T, Hashizume N, Otagiri K, Shoin K, Watanabe N, Karube K, Nakajima H, Saigusa T, Miyashita Y, Yui H, Maruyama S, Kashiwagi D, Nagae A, Okada A, Motoki H, Kuwahara K. Impact of History of Cerebro-Vascular Disease to the Long-Term Outcomes After Percutaneous Coronary Intervention : Insights From the SHINANO 5Years Registry. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Nakamura C, Ebisawa S, Miura T, Senda K, Taki M, Kobayashi M, Kanai M, Okuma Y, Yanagisawa T, Hashizume N, Otagiri K, Shoin K, Watanabe N, Karube K, Nakajima H, Saigusa T, Miyashita Y, Maruyama S, Tabata H, Kashiwagi D, Nagae A, Sakai T, Kato T, Motoki H, Kuwahara K. Impact of Onsite Cardiac Surgical Cover on Long-Term Outcomes of Patients Who Underwent Percutaneous Coronary Intervention : From Shinano 5-years Registry. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Maruyama S, Miura T, Senda K, Taki M, Kobayashi M, Kanai M, Nomi H, Hashizume N, Otagiri K, Miyashita Y, Nishikawa K, Sunohara D, Yui H, Nakamura C, Tabata H, Kashiwagi D, Kobayashi H, Nagae A, Sakai T, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Impact of Nutritional Index For Long Term Outcome of Elderly Patients With Coronary Artery Disease From Subanalysis of the Shinano 5 Years Registry. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Sunohara D, Nagae A, Miura T, Senda K, Taki M, Kobayashi M, Kanai M, Okuma Y, Yanagisawa T, Hashizume N, Otagiri K, Saigusa T, Ebisawa S, Miyashita Y, Yui H, Maruyama S, Nakamura C, Tabata H, Kashiwagi D, Kobayashi H, Sakai T, Kato T, Okada A, Motoki H, Kuwahara K. Long-Term Outcome Comparison of Drug-Eluting Stents and Bare-Metal Stents in Patients With High Bleeding Risk. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Nishikawa K, Nagae A, Miura T, Fujimori K, Sunohara D, Yui H, Maruyama S, Nakamura C, Tabata H, Kashiwagi D, Kobayashi H, Sakai T, Senda K, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Impact of Hyperuricemia on Patients With Diabetes Mellitus Who Underwent Percutaneous Coronary Intervention. American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).2019.3.16-18；USA(New Orleans)
• Okano T, Okada A, Kobayashi H, Shoin W, Yoshie K, Shoda M, Kuwahara K. Relationship between aspiration and body mass index by radiofrequency hot balloon ablation of atrial fibrillation. EHRA 2019.2019.3.17-19；Poryugal(Lisbon)
• Kobayashi H, Okada A, Tabata H, Shoin W, Okano T, Yoshie K, Shoda M, Kuwahara K. Relationship between interatrial septum motion and persistent atrial fibrillation recurrence after catheter ablation. EHRA 2019.2019.3.17-19；Poryugal(Lisbon)
• Saigusa T, Miura T, Taki M, Kobayashi M, Kanai M, Okuma Y, Yanagisawa T, Hashizume N, Otagiri K, Shoin K, Nagae A, Sakai T, Senda K, Kato T, Ebisawa S, Miyashita Y, Motoki H, Kuwahara K. Clinical Characteristics of Late Catch-up Phenomenon after Implantation of 2nd Generation Drug Eluting Stent from SHINANO 5years Registry. ESC Congress 2019. 2019.8.31-9.4；France(Paris)
• Nagae A, Nishikawa K, Fujimori K, Mochidome T, Miura T, Hirabayashi M, Miyashita Y, Yokota D, Yanagisawa T, Hasegawa T, Machida K, Wakabayashi S, Abe N, Karube K, Otagiri K, Sunohara D, Yui H, Maruyama S, Nakamura C, Tabata H, Kashiwagi D, Kobayashi H, Sakai T, Senda K, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. The Impact of diabetes on patients with frail after endovascular treatments: From I-PAD Registry. ESC Congress 2019. 2019.8.31-9.4；France(Paris)
• Nishikawa K, Nagae A, Miura T, Kato T, Hirabayashi M, Miyashita Y, Kashiwagi D, Mochidome T, Sakai T, Senda K, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K.  ESC Congress 2019. 2019.8.31-9.4；France(Paris)
• Fujimori K, Nagae A, Miura T, Hirabayashi M, Yokota D, Yanagisawa T, Hasegawa T, Machida K, Wakabayashi S, Abe N, Karube K, Otagiri K, Tanaka K, Taki M, Morita T, Takahashi W, Nishikawa K, Sunohara D, Yui H, Maruyama S, Nakamura C, Tabata H, Kashiwagi D, Shoin W, Kobayasi H, Okano T, Kimura K, Yoshie K, Sakai T, Senda K, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Impact of Left Ventricular Ejection Fraction in Patients with Peripheral Artery Disease : From I-PAD Registry. ESC Congress 2019. 2019.8.31-9.4；France(Paris)
• Fujimori K, Nagae A, Miura T, Hirabayashi M, Yokota D, Yanagisawa T, Hasegawa T, Machida K, Wakabayashi S, Abe N, Karube K, Otagiri K, Tanaka K, Taki M, Morita T, Takahashi W, Nishikawa K, Sunohara D, Yui H, Maruyama S, Nakamura C, Tabata H, Kashiwagi D, Shoin W, Kobayasi H, Okano T, Kimura K, Yoshie K, Sakai T, Senda K, Kato T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K. Impact of Left Ventricular Ejection Fraction in Patients with Critical Limb Ischemia : From I-PAD Registry. ESC Congress 2019. 2019.8.31-9.4；France(Paris)
• Okada A, Shoda M, Tabata H, Shoin W, Kobayashi H, Okano T, Yoshie K Kuwahara K. Safety and efficacy of percutaneous lead extraction of cardiac implantable electric devices in the elderly. 12th ASIA PACIFIC HEART RHYTHM SOCIETY SCIENTIFIC SESSION (APHRS 2019). 2019.10.24-27；Thailand
• Koyama J, Minamisawa M, Kuwahara K. Arrest of progression of cardiac amyloidosis after chemotherapy predicts favorable outcome in patients with light-chain amyloidosis. ESC Asia with APSC&AFC. 2019.11.8-10；Singapore

〈国立研究開発法人日本医療研究開発機構（AMED）〉
循環器疾患・糖尿病等生活習慣病対策実用化研究事業
桑原宏一郎　代表

高齢心不全患者の多剤併用および薬剤性有害事象に関する診療実態調査
2018～2020年度